Statin use for the primary prevention of cardiovascular disease in adults: updated evidence report and systematic review for the US Preventive Services Task Force

R Chou, A Cantor, T Dana, J Wagner, AY Ahmed, R Fu… - Jama, 2022 - jamanetwork.com
Importance A 2016 review for the US Preventive Services Task Force (USPSTF) found use
of statins for primary prevention of cardiovascular disease (CVD) was associated with
reduced mortality and cardiovascular outcomes. Objective To update the 2016 review on
statins for primary prevention of CVD to inform the USPSTF Data Sources Ovid MEDLINE,
Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic
Reviews (to November 2021); surveillance through May 20, 2022. Study Selection …